editorial
Wednesday, May 31st, 2023

 

Volume 30
October 2008
Number 5

 
Reflection on the Past, Present and Future of Analytical and Quantitative Cytology and Histology

   
Analytical and Quantitative Cytology and Histology (AQCH), whose 2007 Impact Factor is 2.940, has a long history of publishing leading research in cell biology, pathology and oncology based on analytical and quantitative methods.
    Table I categorizes the articles published by AQCH by general topic for the years 2006–2007.1-100 Image analysis, flow cytometry, immunohistochemistry, advanced statistics, human tumor pathology and oncology, related in particular to urinary system and male genital organs, continue to be significant components of articles published over these years. AQCH has also become the publication venue of studies describing new molecular and genetic findings of human cancers and of studies demonstrating advances in risk assessment, detection, diagnosis and prognostic indications.
    

    
    AQCH owes its scientific position to the publication of those research reports that are definitive in their outcomes and represent a pivotal position within our goal for knowledge and understanding. This places an implicit obligation on the reviewers and the Editorial Board to be robust and cogent in their consideration of which articles should be published. Most researchers are passionate about their science, and peer review can be a gruelling process. However, it is only through rigorous review by other experts in the field that we can have confidence in what is published. The next time a reviewer asks for that extra experiment to be performed or data to be gathered prior to publication, please embrace the opportunity to strengthen your paper and other researchers’ perception of it rather than consider it an encumbrance.
    The fundamental principle of publishing definitive studies of the highest quality with a pivotal impact in the area will remain the goal of AQCH. Like most things in life, evolution and development will be required if AQCH is to maintain its position within the literature of cell biology, pathology and oncology. We hope that researchers and readers will feel a sense of common ownership of AQCH in the course of their activities as both authors and reviewers. We will always be pleased to receive suggestions and comments for AQCH as we move forward in our quest for scientific knowledge and understanding.

Rodolfo Montironi, M.D., F.R.C.Path.
Roberta Mazzucchelli, M.D., Ph.D.
From Section of Pathological Anatomy, Polytechnic University of the Marche Region, School of Medicine, United Hospitals, Via Conca 71, I–60126 Torrette, Ancona, Italy (r.montironi@univpm.it).

   
References

  1. Adley BP, Yang XJ: Application of alpha-methylacyl coenzyme A racemase immunohistochemistry in the diagnosis of prostate cancer: A review. Anal Quant Cytol Histol 2006;28:1–13
  2. Kahn E, Vejux A, Ménétrier F, Maiza C, Hammann A, Sequeira-Le Grand A, Frouin F, Tourneur Y, Brau F, Riedinger JM, Steinmetz E, Todd-Pokropek A, Lizard G: Analysis of CD36 expression on human monocytic cells and atherosclerotic tissue sections with quantum dots: Investigation by flow cytometry and spectral imaging microscopy. Anal Quant Cytol Histol 2006;28:14–26
  3. Kayser G, Radziszowski D, Bzdyl P, Sommer R, Kayser K: Theory and implementation of an electronic, automated measurement system for images obtained from immunohistochemically stained slides. Anal Quant Cytol Histol 2006;28:27–38
  4. Katona TM, Shienbaum AJ, Wyatt LL, Brown GA, Cheng L: Malignant fibrous histiocytoma of the glans penis: A case report. Anal Quant Cytol Histol 2006;28:39–42
  5. Tolivia J, Navarro A, del Valle E, Perez C, Ordoñez C, Martínez E: Application of Photoshop and Scion Image analysis to quantification of signals in histochemistry, immunocytochemistry and hybridocytochemistry. Anal Quant Cytol Histol 2006;28:43–53
  6. Razga Z, Randel Nyengaard J: A stereologic approach to estimate the number of immunogold-labeled molecules in cells of tubules. Anal Quant Cytol Histol 2006;28:54–60
  7. Scartozzi M, Pierantoni C, Berardi R, Antognoli S, Bearzi I, Cascinu S: Epidermal growth factor receptor: A promising therapeutic target for colorectal cancer. Anal Quant Cytol Histol 2006;28:61–68
  8. Nafe R, Yan B, Schlote W, Schneider B: Application of different methods for nuclear shape analysis with special reference to the differentiation of brain tumors. Anal Quant Cytol Histol 2006;28:69–77
  9. Boon ME, Berger TH, Middag-Broekman AJ, Kok LP: Optimized quality of histologic images allows the use of neural network scanning in diagnosis of fungal infection of abnormal nails. Anal Quant Cytol Histol 2006;28:78–86
  10. Nieuwenhuizen L, Khalil MK, Venkatesh N, Othman NH: Endometrial and endocervical secretion: The search for histochemical differentiation. Anal Quant Cytol Histol 2006;28:87–96
  11. Nyagol J, Nyong’o A, Byakika B, Muchiri L, Cocco M, de Santi MM, Spina D, Bellan C, Lazzi S, Kostopoulos I, Luzi P, Leoncini L: Routine assessment of hormonal receptor and her-2/neu status underscores the need for more therapeutic targets in Kenyan women with breast cancer. Anal Quant Cytol Histol 2006;28:97–103
  12. Samaratunga H, Gardiner RA, Yaxley J, Brown I: Atypical prostatic glandular proliferations on needle biopsy: Diagnostic implications, use of immunohistochemistry, and clinical significance. Anal Quant Cytol Histol 2006;28:104–110
  13. Lopez-Beltran A, MacLennan GT, Montironi R: Cyclin E as molecular marker in the management of breast cancer: A review. Anal Quant Cytol Histol 2006;28:111–114
  14. Zheng WQ, Ma R, Zheng JM, Gong ZJ: Elastin distribution in the normal uterus, uterine leiomyomas, adenomyosis and adenomyomas: A comparison. Anal Quant Cytol Histol 2006;28:115–120
  15. Matsuda T, Fujime M, Suda K: Relationship between the prostatic tissue components and natural history of benign prostatic hyperplasia. Anal Quant Cytol Histol 2006;28:121–124
  16. Zhou M, Magi-Galluzzi C, Epstein JI: Prostate basal cell lesions can be negative for basal cell keratins: A diagnostic pitfall. Anal Quant Cytol Histol 2006;28:125–129
  17. Rocher AE, Gonzalez A, Palaoro LA, Blanco AM: Usefulness of AgNOR technique and CEA expression in atypical metaplastic cells from cervical smears. Anal Quant Cytol Histol 2006;28:130–136
  18. Bearzi I, Mandolesi A, Arduini F, Costagliola A, Ranaldi R: Gastrointestinal stromal tumor. A study of 158 cases: Clinicopathological features and prognostic factors. Anal Quant Cytol Histol 2006;28:137–147
  19. Zeppa P, Marino G, Lepore M, Troncone G, Lupoli GA, Biondi B, Picardi M, Pane F, Vetrani A, Palombini L: Flow cytometry phenotypization of thyroidal lymphoid infiltrate and functional status in Hashimoto’s thyroiditis. Anal Quant Cytol Histol 2006;28:148–156
  20. del Vecchio MT, Epistolato MC, Tripodi SA, Montironi R, Giordano A: Intratubular germ cell neoplasia of unclassified type. Anal Quant Cytol Histol 2006;28:157–170
  21. Gammon RR, Kharazi M, Brandt JT, Keyhani-Rofagha S: Correlation between the Papanicolaou stain and the Wright-Giemsa stain in body fluids: A quality assurance study. Anal Quant Cytol Histol 2006;28:171–174
  22. Pawitan JA, Suryono IA: Sensitivity and specificity of the micronucleus test in hypotonic-swollen mononuclear leukocytes compared to the micronucleus test in binucleated lymphocytes to assess chromosomal breaks. Anal Quant Cytol Histol 2006;28:175–180
  23. Camargo RS, Shirata NK, di Loreto C, Garcia EA, Castelo A, Longatto Filho A: Significance of AgNOR measurement in thyroid lesions. Anal Quant Cytol Histol 2006;28:188–192
  24. Iczkowski KA, Butler SL: New immunohistochemical markers in testicular tumors. Anal Quant Cytol Histol 2006;28:181–187
  25. Katona TM, Lopez-Beltran A, MacLennan GT, Cheng L, Montironi R, Cheng L: Soft tissue tumors of the penis: A review. Anal Quant Cytol Histol 2006;28:193–206
  26. Aktug H, Uslu S, Terek MC, Terzi H, Turgut M, Ozsener S, Bilgin O: Effects of ovariectomy and tamoxifen on rat bone tissue: Histomorphometric and histopathologic study. Anal Quant Cytol Histol 2006;28:207–212
  27. Chowdhury N, Pai MR, Lobo FD, Kini H, Varghese R: Interobserver variation in breast cancer grading: A statistical modeling approach. Anal Quant Cytol Histol 2006;28:213–218
  28. Auada MP, Adam RL, Leite NJ, Puzzi MB, Cintra ML, Rizzo WB, Metze K: Texture analysis of the epidermis based on fast Fourier transformation in Sjögren-Larsson syndrome. Anal Quant Cytol Histol 2006;28:219–227
  29. Adley BP, Papavero V, Sugimura J, Teh BT, Yang XJ: Diagnostic value of cytokeratin 7 and parvalbumin in differentiating chromophobe renal cell carcinoma from renal oncocytoma. Anal Quant Cytol Histol 2006;28:228–236
  30. Demiriz M, Kurumlu Z, Celasun B, Günhan O: A simple method for the evaluation of epidermal thickness variations in psoriasis vulgaris. Anal Quant Cytol Histol 2006;28:237–242
  31. Bartels PH, Ranger-Moore J, Alberts D, Hess L, Scarpelli M, Montironi R: Carcinogenesis and the hypothesis of phylogenetic reversion. Anal Quant Cytol Histol 2006;28:243–252
  32. Model MA, Blank JL: Intensity calibration of a laser scanning confocal microscope based on concentrated dyes. Anal Quant Cytol Histol 2006;28:253–261
  33. Rode M, Flezar MS, Kogoj-Rode M, Us-Krasovec M: Image cytometric evaluation of nuclear texture features and DNA content of the reticular form of oral lichen planus. Anal Quant Cytol Histol 2006;28:262–268
  34. Klimek I, Kaluzynski A, Kulig A, Szymczak W, Ambroziak R: Glomerular basement membrane thinning in children: A morphometric assessment. Anal Quant Cytol Histol 2006;28:269–280
  35. Markiewicz T, Osowski S, Patera J, Kozlowski W: Image processing for accurate cell recognition and count on histologic slides. Anal Quant Cytol Histol 2006;28:281–291
  36. Nair BC, Kumar S, Rani S, Paliwal OP: Analysis of karyometric variables in spontaneously occurring canine mammary tumors. Anal Quant Cytol Histol 2006;28:292–296
  37. Petroff BK, Phillips TA, Kimler BF, Fabian CJ: Detection of biomarker gene expression by real-time polymerase chain reaction using amplified ribonucleic acids from formalin-fixed random periareolar fine needle aspirates of human breast tissue. Anal Quant Cytol Histol 2006;28:297–302
  38. Yalçin B, Arda N, Tezel GG, Erman M, Alli N: Expressions of vascular endothelial growth factor and CD34 in oral aphthous lesions of Behçet’s disease. Anal Quant Cytol Histol 2006;28:303–306
  39. Wu HS, Salzberg SP, Gil J: Automatic image segmentation with linear clustering for quantification of neointimal formation after surgical vein grafting. Anal Quant Cytol Histol 2006;28:307–315
  40. Kahn E, Ménétrier F, Vejux A, Montange T, Dumas D, Riedinger JM, Frouin F, Tourneur Y, Brau F, Stoltz JF, Lizard G: Flow cytometry and spectral imaging multiphoton microscopy analysis of CD36 expression with quantum dots 605 of untreated and 7-ketocholesterol-treated human monocytic cells. Anal Quant Cytol Histol 2006;28:316–330
  41. Han U, Adabaˇg A, Köyba¸sioˇglu F, Onal BU: Clinical value of cell counts and indices in testicular fine needle aspiration cytology in primary infertility: Diagnostic performance compared with histology. Anal Quant Cytol Histol 2006;28:331–336
  42. Davidson DD, Cheng L: “Field cancerization” in the urothelium of the bladder. Anal Quant Cytol Histol 2006;28:337–338
  43. Lopez-Beltran A: Urothelial changes induced by therapeutic procedures for bladder cancer. Anal Quant Cytol Histol 2006;28:339
  44. Mazzucchelli R, Tuna B: Noninvasive urothelial neoplasms: Which classification? Anal Quant Cytol Histol 2006;28:340
  45. Model MA, Blank JL: Difference between mean and threshold as a measure of intensity in confocal microscopy images. Anal Quant Cytol Histol 2006;28:341–343
  46. Bargaje A, Venkataraman G, Flanigan R, Wojcik EM, Ananthanarayanan V: Utility of prostate biopsy morphometric sum optical density for identifying extraprostatic extension on subsequent prostatectomy. Anal Quant Cytol Histol 2006;28:343–345
  47. van Bogaert LJ: Sampling of sentinel nodes: A simulation study. Anal Quant Cytol Histol 2006;28:345–346
  48. Vidal-Jimenez A: Gleason grading of prostate cancer in needle biopsies vs. radical prostatectomy specimens. Anal Quant Cytol Histol 2006;28:340–341
  49. Artacho-Pérula E, Insausti R: Quantitative estimations of the entorhinal cortex in Alzheimer’s disease. Anal Quant Cytol Histol 2007;29:1–16
  50. Orr JA, Hamilton PW: Histone acetylation and chromatin pattern in cancer: A review. Anal Quant Cytol Histol 2007;29:17–31
  51. Hellström M, Lexander H, Franzén B, Egevad L: Proteomics in prostate cancer research. Anal Quant Cytol Histol 2007;29:32–40
  52. Martignoni G, Brunelli M, Gobbo S, Remo A, Ficarra V, Cossu-Rocca P, Pea M, Chilosi M, Menestrina F, Cheng L: Role of molecular markers in diagnosis and prognosis of renal cell carcinoma. Anal Quant Cytol Histol 2007;29:41–49
  53. Aktug H, Ozdedeli K, Altay B, Cüreklibatur I, Turna B, Yilmaz O: Consequences of epididymal ligation on prepubertal rats. Anal Quant Cytol Histol 2007;29:50–56
  54. Pignataro L, Pagani D, Brando B, Sambataro G, Scarpati B, Corsi MM: Down-regulation of zeta chain and zeta-associated protein 70 (Zap 70) expression in circulating T lymphocytes in laryngeal squamous cell carcinoma. Anal Quant Cytol Histol 2007;29:57–62
  55. Bartels PH, Fabian CJ, Kimler BF, Ranger-Moore JR, Frank DH, Yozwiak ML, Alberts DS: Karyometry of breast epithelial cells acquired by random periareolar fine needle  aspiration in women at high risk for breast cancer. Anal Quant Cytol Histol 2007;29:63–70
  56. Lopez-Beltran A, Maclennan GT, de la Haba-Rodriguez J, Montironi R, Cheng L: Research advances in apoptosis-mediated cancer therapy: A review. Anal Quant Cytol Histol 2007;29:71–78
  57. Prayer-Galetti T, Gardiman M, Sacco E, Fracalanza S, Betto G, Pinto F: Finding of no tumor (pT0) in patients undergoing radical retropubic prostatectomy for clinically localized prostate cancer. Anal Quant Cytol Histol 2007;29:79–86
  58. Shapiro NA, Poloz TL, Shkurupij VA, Tarkov MS, Poloz VV, Demin AV: Application of artificial neural network for classification of thyroid follicular tumors. Anal Quant Cytol Histol 2007;29:87–94
  59. Ates U, Baka M, Turgut M, Uyanikgil Y, Ulker S, Yilmaz O, Tavmergen E, Yurtseven M: Light, electron microscopic and immunohistochemical study of the effect of low-dose aspirin during the proestrus phase on rat endometrium in the preimplantation period. Anal Quant Cytol Histol 2007;29:95–102
  60. Qian W, Zhukov T, Song D, Tockman MS: Computerized analysis of cellular features and biomarkers for cytologic diagnosis of early lung cancer. Anal Quant Cytol Histol 2007;29:103–111
  61. Powell KA, Nakamoto C, Villarruel S, Boehm C, Muschler G: Quantitative image analysis of connective tissue progenitors. Anal Quant Cytol Histol 2007;29:112–121
  62. Lopez-Beltran A: Immunohistochemical markers in evaluation of urinary and bladder tumors. Anal Quant Cytol Histol 2007;29:121–122
  63. Huang J, Wu C, di Sant’Agnese PA, Yao JL, Cheng L, Na Y: Function and molecular mechanisms of neuroendocrine cells in prostate cancer. Anal Quant Cytol Histol 2007;29:128–138
  64. Colecchia M, Nistal M, Gonzalez-Peramato P, Carmignani L, Salvioni R, Nicolai N, Regadera J: Leydig cell tumor and hyperplasia: A review. Anal Quant Cytol Histol 2007;29:139–147
  65. Kararizou EG, Manta P, Kalfakis N, Gkiatas KA, Vassilopoulos D: Morphologic and morphometrical study of the muscle spindle in muscular dystrophy. Anal Quant Cytol Histol 2007;29:148–152
  66. Gamsizkan M, Demiriz M, Karslioˇglu Y, Günhan O: Comparative morphometric analysis of intraepidermal and dermal lymphocytes in early mycosis fungoides and some inflammatory dermatoses. Anal Quant Cytol Histol 2007;29:153–158
  67. Ozcan A, Karslioglu Y, Kurt B, Onguru O, Gunhan O: Quantitative evaluation of immunohistochemical staining in gastrointestinal stromal tumors. Anal Quant Cytol Histol 2007;29:159–165
  68. Shao L, Zhu Q, Feng W, He M, Li G, Zeng H, Zou J: Observation of microvasculature in intestinal wall after burn in rats. Anal Quant Cytol Histol 2007;29:166–172
  69. Rayat CS, Joshi K, Dey P, Sakhuja V, Minz RW, Datta U: Glomerular morphometry in biopsy evaluation of minimal change disease, membranous glomerulonephritis, thin basement membrane disease and Alport’s syndrome. Anal Quant Cytol Histol 2007;29:173–182
  70. Bhatia A, Dey P, Kumar Y: Morphometry of urinary atypical cells. Anal Quant Cytol Histol 2007;29:183–184
  71. Montironi R, Mazzucchelli R: Analytical and Qualitative Cytology and Histology: Reflection on the past two years. Anal Quant Cytol Histol 2007;29:123–127
  72. Velazquez EF, Cubilla AL: Penile squamous cell carcinoma: Anatomic, pathologic and viral studies in Paraguay (1993–2007). Anal Quant Cytol Histol 2007;29:185–198
  73. Nafe R, Glienke W, Hattingen E, Schlote W, Lanfermann H, Zanella F: Correlation between amplification of the gene for the epidermal growth factor receptor (EGFR), data from preoperative proton-MR-spectroscopy (1HMRS) and histomorphometric data of glioblastomas. Anal Quant Cytol Histol 2007;29:199–207
  74. Razga Z, Nyengaard JR: Estimation of the number of angiotensin II AT1 receptors in rat kidney afferent and efferent arterioles. Anal Quant Cytol Histol 2007;29:208–216
  75. Rehnberg J, Zendehrokh N, Dejmek A: Lower proliferation rate in metastatic effusion mesothelial cells than in benign effusions. Anal Quant Cytol Histol 2007;29:217–220
  76. Yang Y, Zhang L, Wei Y, Wang H, Xiong W, Chen Z, Hes O, Zheng J: Detection of EWSR1 translocation with nuclear extraction-based fluorescence in situ hybridization for diagnosis of Ewing’s sarcoma/primitive neuroectodermal tumor. Anal Quant Cytol Histol 2007;29:221–230
  77. Gedoz L, Lauxen Ida S, Sant’Ana MF, Rados PV: Proliferative activity in clinically healthy oral mucosa exposed to tobacco smoking and alcohol: A longitudinal study using the agNOR staining technique. Anal Quant Cytol Histol 2007;29:231–238
  78. Layfield LJ, Lewis C: In situ and invasive components of mammary adenocarcinoma: Comparison of Her-2/neu status. Anal Quant Cytol Histol 2007;29:239–243
  79. Boyles TH, Johnson S, Garrahan N, Freedman AR, Williams GT: A validated method for quantifying macrovesicular hepatic steatosis in chronic hepatitis C. Anal Quant Cytol Histol 2007;29:244–250
  80. Wiltgen M, Gerger A, Wagner C, Bergthaler P, Smolle J: Evaluation of texture features in spatial and frequency domain for automatic discrimination of histologic tissue. Anal Quant Cytol Histol 2007;29:251–263
  81. Proca DM, Williams JD, Rofagha S, Tranovich VL, Keyhani-Rofagha S: Improved rate of high-grade cervical intraepithelial neoplasia detection in human papillomavirus DNA hybrid capture testing. Anal Quant Cytol Histol 2007;29:264–270
  82. Pavlopoulos PM, Zimeras S, Kavantzas N, Korkolopoulou P, Agapitos E, Patsouris E: Segmentation of transitional cell carcinoma nuclei by nonsupervised thresholding in different color spaces. Anal Quant Cytol Histol 2007;29:271–278
  83. Einenkel J, Braumann UD, Horn LC, Kuska JP, Höckel M: 3-D analysis of the invasion front in squamous cell carcinoma of the uterine cervix: Histopathologic evidence for collective invasion per continuitatem. Anal Quant Cytol Histol 2007;29:279–290
  84. Ergin K, Aktug H, Basloglu H, Basaloglu HK, Yilmaz MI, Turgut M: The effect of leptin on adrenal glands in rats with streptozotocin-induced diabetes: An experimental study. Anal Quant Cytol Histol 2007;29:291–295
  85. Kayser K, Kayser G, Metze K: The concept of structural entropy in tissue-based diagnosis. Anal Quant Cytol Histol 2007;29:296–308
  86. Ondracek RP, Parker F, Allen A, Davis W, Ray M, McCann W, Marshall JR: Standardization of nuclear morphometry-based biomarkers. Anal Quant Cytol Histol 2007;29:309–316
  87. Uslu S, Uysal A, Oktem G, Yurtseven M, Tanyalçin T, Basdemir G: Constructive effect of exogenous melatonin against osteoporosis after ovariectomy in rats. Anal Quant Cytol Histol 2007;29:317–325
  88. Smith FB, Aksenov S: Potential role of nuclear appearance in pathologic recognition and delimitation of sessile serrated polyps of the colon: A karyometric study. Anal Quant Cytol Histol 2007;29:326–332
  89. Abraham MG, Levin KA, Balasubramanian M, Minimo C, Galindo LM, Hou JS: Diagnosis of T-cell lymphoma in body fluids: Cytologic features and unusual flow cytometric findings. Anal Quant Cytol Histol 2007;29:333–338
  90. Mazzucchelli R, Barbisan F, Galosi AB: Finding of no tumor (pT0) in patients undergoing radical retropubic prostatectomy for clinically localized prostate cancer. Anal Quant Cytol Histol 2007;29:339–340
  91. Wagner DG, Yao JL, di Sant’Agnese PA, Cheng L, Lopez-Beltran A, Montironi R, Huang J: Soft tissue tumors of the prostate: A review. Anal Quant Cytol Histol 2007;29:341–350
  92. Chadwick B, Willmore-Payne C, Holden J, Layfield L: Fluorescence in situ hybridization determination of aneusomy: Criteria and technical considerations. Anal Quant Cytol Histol 2007;29:351–357
  93. Yalçin B, Tezel GG, Arda N, Erman M, Alli N: Vascular endothelial growth factor, vascular endothelial growth factor receptor-3 and cyclooxygenase-2 expression in psoriasis. Anal Quant Cytol Histol 2007;29:358–364
  94. Herrera Espiñeira C, Fernández Valdivia J, López-Cuervo JE, Martínez Tapias J: Textural analysis in the diagnosis of benign and malignant breast cells. Anal Quant Cytol Histol 2007;29:365–369
  95. Lamba A, Dey P, Kumari S, Marwaha N: Prognostic significance of the histomorphometric features of bone marrow trephine biopsies in patients with chronic myeloid leukemia. Anal Quant Cytol Histol 2007;29:370–376
  96. Vidal-Jimenez A: New immunohistochemical markers in testicular tumors. Anal Quant Cytol Histol 2007;29:377
  97. Blanca A, Requena MJ, Carrasco JC: Carcinogenesis and the hypothesis of phylogenetic reversion. Anal Quant Cytol Histol 2007;29:379–380
  98. Requena MJ, Alvarez-Kindelan J, Blanca A: Immunohistochemical markers in the evaluation of tumors of the urinary bladder: A review. Anal Quant Cytol Histol 2007;29:380–382
  99. Deveci E: Light and electron microscopic study of intestinal ischemia-reperfusion in the rat. Anal Quant Cytol Histol 2007;29:382
  100. Pospihalj B, Zamparese R, Mazzucchelli R, Morichetti D: Kidney cancer: Not a single disease. Anal Quant Cytol Histol 2007;29:377–379
Financial Disclosure: The authors have no connection to any companies or products mentioned in this editorial.

Keywords: publishing, research. (Anal Quant Cytol Histol 2008;30:249–253)



  
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